Alright, I've seen Futurama, Simpsons, Clone High, Family Guy and Cowboy Bebop. I'll suggest some shows and include where they legally reside [in the US]. (There are other ways but I'll leave those to the communities about that.) I'm not sure our tastes are very similar and these are mostly known, I don't tend to know obscure things, so you may have already tried them all; but-

Pantheon - Sci-Fi - Prime Video - season 2 airing now

A lot of what you mentioned is comedy, whereas this one is serious but it is a sci-fi, like a few of the shows you like. I think it's pretty solid but I'll warn that it doesn't feel binge-able because it's a bit intense.

Central Park - Musical Sit-Com - Apple TV+ - 3 seasons - neither renewed nor canceled

You didn't mention Bob's Burgers, but this is from the same creator/studio. You mentioned early Simpsons so maybe you'd like this, though that depends on your feeling towards musicals too.

F is for Family - Sit-Com - Netflix - 5 seasons - Ended

Unlike Central Park, this one is more in line with Family Guy. It's more raunchy than the other sit-coms on this list, but it's also got a 70s setting that gives it a good feel and some uniqueness.

Close Enough - Sit-Com - VOD purchase amazon/apple/vudu - 3 seasons - Canceled

From the creator of Regular Show. This one is shorter episodes and pretty much just comedy and a bit surreal.

Bless the Harts - Sit-Com - Hulu - 2 seasons - Canceled

This is another more wholesome sit-com, it's also a bit more southern. You didn't mention King of the Hill; but if you liked any of that, you'd maybe like this. It's mostly grounded and only occasionally a bit over the top. The first season is better than the second, in my opinion.

Inside Job - Sci-Fi Sit-Com - Netflix - 2 parts - Canceled

I kind of mostly mention this one because I feel like it got more solid praise than a lot of recent adult animation. Seems like everything that comes out faces very mixed reviews but most people seemed to like this one.

Captain Fall - Dark Comedy - Netflix - 1 season - neither renewed nor canceled

This one I'll admit is a complete shot in the dark and I'm probably way off base here- I never really got into the Venture Bros but when I see clips of that and the trailer for this they give me the same sort of uninterested feeling. I don't think the plot-lines are really all that similar but they both feel, idk action-y. It's similar to how I feel about Archer too- I don't tend to get into action/spy/adventure like things much.

Anyway, if you are ever looking for suggestions you can def make a post anytime, other people probably know shows I don't. Or maybe some show that isn't out yet will be more your speed in the future. It seems like adult animation might be on the rise, so maybe, never know.

I'm kind of curious what your like top 5-ish animated adult shows are. Obviously this community is for any/all adult animation, past and present. If you're looking for something new to watch maybe you can make a post. I can't guarentee engagement but perhaps somebody knows something more to your tastes that you haven't seen yet.

I'm not entirely sure if this is the kind of thing you are talking about but I find something about sweaters / cardigans / sweater vests seem to lend themselves to a more cute look. To an extent I think so do things that might be considered nerdy like button up shirts / glasses / suspenders. Also colors that are usually considered more feminine but styled in a masculine way like pinks and purples.

Some sweater examples tv/celeb/animation:

Spencer (Criminal Minds) cardigan https://pbs.twimg.com/media/EyBVIIJW8AA3nz8.jpg

David (Schitt's Creek) fuzzy sweater https://www.goldderby.com/wp-content/uploads/2020/10/danlevy.jpg

Clark (My Adventures with Superman) sweater https://nypost.com/wp-content/uploads/sites/2/2023/06/NYPICHPDPICT000013326225.jpg?w=1024

Sylvester (Scorpion) sweater vest https://static.wikia.nocookie.net/scorpion2011/images/2/27/Sylvester.png/revision/latest?cb=20170506031456

Daniel Radcliffe in sweater https://www.iwmbuzz.com/wp-content/uploads/2022/03/aww-dorable-cutest-photos-of-daniel-radcliffe-that-we-can-never-forget-3.jpg